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KMID : 0363220070450030237
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Korean Journal of Dermatology
2007 Volume.45 No. 3 p.237 ~ p.241
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Photodynamic Therapy for Treatment of Bowen`s Disease
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Kim Yun-Jeon
Kang Hee-Young
Lee Eun-So
Kim You-Chan
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Abstract
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Background: Photodynamic therapy (PDT) is increasingly used for superficial skin cancers. However, there have only been a few reports on Bowen’s disease treated with PDT in the Korean literature.
Objective: The purpose of this study was to evaluate the effectiveness and side effects of PDT in the treatment of Bowen’s disease.
Methods: We treated 20 Bowen’s disease lesions in 15 patients using topical PDT containing 5-aminolaevulinic acid and a light-emitting diode device. The light intensity used was 100 mW/cm2 and the dosage was 140~220 J/cm2.
Results: Complete clearance was achieved in 17 of 20 lesions (85%) after 2~4 treatment sessions. The only side effect was a stinging sensation, which occurred in 5 lesions (20%).
Conclusion: PDT is a relatively effective and useful alternative therapy for treatment of Bowen’s disease.
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KEYWORD
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Bowen`s disease, Photodynamic therapy
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